Can coffee help prevent Covid 19?

Recent research published in Cell & Bioscience by Chen-Shiou Wu and colleagues explores the potential of coffee consumption as a strategy to reduce the risk of a Covid 19 infection.

What was the Study?

This study delves into the mechanisms by which coffee may reduce the risk of COVID-19, focusing on the interaction between coffee compounds and the virus.

Previous studies have linked coffee consumption with reduced COVID-19 risk and severity, but the exact mechanisms were unclear.

A human trial involving 64 subjects was conducted.

The trial found that consuming approximately 1–2 cups of coffee per day was sufficient to inhibit infection from multiple variants of SARS-CoV-2.

Moderate coffee consumption may serve as a preventive measure against SARS-CoV-2 infection by interfering with the virus’s ability to enter human cells.

For those who are sensitive to caffeine or prefer to avoid it, decaffeinated coffee still offers protective benefits against the virus.

Incorporating 1–2 cups of coffee into daily dietary routines could be an effective strategy to enhance immunity against SARS-CoV-2.

What were the conclusions of the Study?

The study identified that coffee can inhibit multiple variants of SARS-CoV-2 by restricting the binding of the virus's spike protein to human angiotensin-converting enzyme 2 (ACE2).

This thereby reducing the activity of transmembrane serine protease 2 (TMPRSS2) and cathepsin L (CTSL), which are essential for viral entry into cells.

Isochlorogenic acid A, B, and C, found in coffee, showed significant potential to inhibit Covid 19 infections with an efficiency of 43–54%.

The study also found that decaffeinated coffee retains inhibitory activity against SARS-CoV-2, making it a viable option for those avoiding caffeine.

So, the research by Chen-Shiou Wu and colleagues provides compelling evidence that coffee consumption can play a role in preventing Covid 19 infections.

By inhibiting the virus's entry into human cells and maintaining these benefits, even in decaffeinated coffee, emerges as a practical dietary strategy in the ongoing fight against COVID-19.

Note: This information is intended to support, not replace, discussions with your doctor or healthcare professionals. Always consult with your healthcare provider for personalized medical advice and treatment plans.